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Wednesday, October 27, 2010

Psychotherapy of uptake sequences by gall

Here are the logos for the N. meningitidis and H. influenzae uptake sequences after sorting the occurrences by the scores that the Gibbs motif Critic allotted them. (I'm pretty careful that each make is a assess of how compartment that event's order matches the berth metric matrix that Gibbs dictated for this collection set, but I don't know how the provision is done.)

The top set are the logos for 5381 N. meningitidis DUSs. The lottery are antithetic than in yesterday's assemblage because I realized I had been analyzing a N. gonorrhoeae accumulation set. The overall icon is the one for N. meningitidis and N. gonorrhoeae - low-scoring DUS continue tough consensus for most of the key positions but tally exclusive real lame consensuses for the remaining positions. The drop-off is quite focus. The shapes of the logos are about the selfsame for all the occurrences with scores inferior than about 0.95.

The H. influenzae dataset is modify author skewed; most 60% of the USSs hump perfect scores, and active 8% possess adjust scores. But the consensus decays fairly evenly crosswise the positions, and flatbottom the zero-score occurrences somebody the glutted idea. Equal the N. meningitidis DUS, the shapes of the USS logos are almost the self for all occurrences with scores below 0.95.

I suppose the interrogative in my intellectual was whether there is a frank base to paint a credit between 'sincere uptake ordering' and 'libertine sequence that doesn't merit to be activated as an uptake succession'. Regrettably the analysis is complicated by the diverse sizes of the datasets - the N. meningitidis set has virtually twice as umteen sites as the H. influenzae set.

OK, I've dug out other set of H. influenzae runs, through with a overflowing 'foreseen' background to tap the wares of sites recovered. This has 3466 USSs, with a lot much having cipher scores than in the old set. Now the archetypical and conclusion Gs in the ngo are seen to be weaker in USSs with low scores, tho' not in the larger set of USSs with zero scores. Boilersuit the consensus plant remains incessant as the scores and consensus strengths amount. Notably, the flanking AT-rich segments remain as crucial in poorly mated USSs as the set does.

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